Glycolysis

Glycolysis

  • First metabolic pathway to give any living organism energy
  • used in every cell- universal
  • organelles are not needed for the process to take place, can occur in both prokaryotes and eukaryotes
  • occurs in the cytosol
  • 10 enzymes in the glycolysis procees, divided into 2 phases, the energy investment phase and the energy generation phase

 

Glucose enters glycolysis to form 2 mols of pyruvate. When oxygen and is available the pyruvate continues into the TCA cycle. Both mitochondria and oxygen much be present for this passage to occur.

However, when no oxygen is available, the pyruvate either forms 2 mols of carbon dioxide and ethanol through fermentation or 2 mols of lactic acid(lactate) which is also through fermentation. Lactate regenerates NAD+ when pyruvate is converted. red blood cells, rich in oxygen but lacking mitochondria use fermentation.

Process of glycolysis

5 enzyme reactions consisting of 2 irreversible reactions and 3 reversible reactions make up the Energy Investment Phase.

5 enzyme reactions consisting of 1 irreversible reactions and 4 reversible reactions make up the Energy Generation Phase.

Net gain of this reaction: 2 ATP and 2 NADH

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s